Arsenal are set to face an Aston Villa side weakened by key departures, while Tottenham hope their £300 million investment in new signings pays off against Newcastle. Liverpool's new manager Andoni Iraola will make his home debut at Anfield against Nottingham Forest, and Manchester United aim to recover from an opening loss when they host Ipswich. Villa have lost several key players, including Ezri Konsa, who may make his Arsenal debut at Villa Park, and Morgan Rogers, who moved to Chelsea for £117 million.
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